Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Trial records in obesity and overweight in adults — page 5

208 records bearing on obesity and overweight in adults.

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Records

208 documents · page 5 of 9

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
MAZ-PH2-OBESITY-REGIONAL-CNprogramme recordMazdutidePhase 3ReportedRandomised, double-blind, placebo-controlled2023Very low
STEP-5SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled3042022High
STEP-8SemaglutidePhase 3ReportedRandomised, double-blind, active-controlled3382022High
SURMOUNT-1TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2,5392022High
STEP-5-PKprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low
STEP-8-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low
SURMOUNT-1-OLEprogramme recordTirzepatidePhase 3ReportedSingle-arm open-label2022Very low
STEP-5-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low
STEP-8-PKprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low
SURMOUNT-1-ELDERLYprogramme recordTirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2022Very low
STEP-5-HEPATIC-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low
STEP-8-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2022Very low
STEP-5-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2022Very low
STEP-8-HEPATIC-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low
STEP-8-BIOMARKERprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2022Very low
STEP-1SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,9612021High
STEP-2SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,2102021High
STEP-3SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled6112021High
STEP-4SemaglutidePhase 3ReportedRandomised withdrawal8032021High
CAGRI-PH2-DOSEFINDCagrilintidePhase 2ReportedDose-finding7062021Moderate
STEP-1-ADHERENCEprogramme recordSemaglutidePhase 3ReportedObservational2021Very low
STEP-2-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2021Very low
STEP-3-ELDERLYprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-4-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2021Very low

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