Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Reported trial records — page 9

644 records with the status reported.

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Records

644 documents · page 9 of 27

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
STEP-2SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,2102021High
STEP-3SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled6112021High
STEP-4SemaglutidePhase 3ReportedRandomised withdrawal8032021High
SURPASS-1TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled4782021High
SURPASS-2TirzepatidePhase 3ReportedRandomised, double-blind, active-controlled1,8792021High
SURPASS-3TirzepatidePhase 3ReportedRandomised, open-label, active-controlled1,4442021High
SURPASS-4TirzepatidePhase 3ReportedRandomised, open-label, active-controlled2,0022021High
CAGRI-PH2-DOSEFINDCagrilintidePhase 2ReportedDose-finding7062021Moderate
AMPLITUDE-OExenatidePhase 3ReportedEvent-driven cardiovascular outcome trial4,0762021Moderate
STEP-1-ADHERENCEprogramme recordSemaglutidePhase 3ReportedObservational2021Very low
STEP-2-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2021Very low
STEP-3-ELDERLYprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-4-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2021Very low
SURPASS-1-RENAL-IMPprogramme recordTirzepatidePhase 1ReportedPhase 1 ascending dose2021Very low
SURPASS-2-ELDERLYprogramme recordTirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
SURPASS-3-DDIprogramme recordTirzepatidePhase 1ReportedRandomised crossover2021Very low
SURPASS-4-PKprogramme recordTirzepatidePhase 1ReportedPhase 1 ascending dose2021Very low
AMPLITUDE-O-REGIONAL-JPprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
CAGRI-PH2-DOSEFIND-PKprogramme recordCagrilintidePhase 1ReportedPhase 1 ascending dose2021Very low
STEP-1-BIOMARKERprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-2-HEPATIC-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2021Very low
STEP-3-OLEprogramme recordSemaglutidePhase 3ReportedSingle-arm open-label2021Very low
STEP-4-PKprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2021Very low
SURPASS-1-PKprogramme recordTirzepatidePhase 1ReportedPhase 1 ascending dose2021Very low

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