Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Trial records reported in 2021

49 records with a recorded report or completion year of 2021.

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Records

49 documents · page 1 of 3

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
AMPLITUDE-OExenatidePhase 3ReportedEvent-driven cardiovascular outcome trial4,0762021Moderate
AMPLITUDE-O-BODY-COMPprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
AMPLITUDE-O-QOLprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
AMPLITUDE-O-REGIONAL-CNprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
AMPLITUDE-O-REGIONAL-JPprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
CAGRI-PH2-DOSEFINDCagrilintidePhase 2ReportedDose-finding7062021Moderate
CAGRI-PH2-DOSEFIND-DDIprogramme recordCagrilintidePhase 1ReportedRandomised crossover2021Very low
CAGRI-PH2-DOSEFIND-HEPATIC-IMPprogramme recordCagrilintidePhase 1ReportedPhase 1 ascending dose2021Very low
CAGRI-PH2-DOSEFIND-PKprogramme recordCagrilintidePhase 1ReportedPhase 1 ascending dose2021Very low
CAGRI-PH2-DOSEFIND-RENAL-IMPprogramme recordCagrilintidePhase 1ReportedPhase 1 ascending dose2021Very low
STEP-1SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,9612021High
STEP-1-ADHERENCEprogramme recordSemaglutidePhase 3ReportedObservational2021Very low
STEP-1-BIOMARKERprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-1-ELDERLYprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-1-OLEprogramme recordSemaglutidePhase 3ReportedSingle-arm open-label2021Very low
STEP-2SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,2102021High
STEP-2-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2021Very low
STEP-2-HEPATIC-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2021Very low
STEP-2-PKprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2021Very low
STEP-2-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2021Very low
STEP-3SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled6112021High
STEP-3-ADHERENCEprogramme recordSemaglutidePhase 3ReportedObservational2021Very low
STEP-3-BIOMARKERprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-3-ELDERLYprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low

page 1 of 3

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