Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Phase 3 trial records — page 5

351 records at phase 3.

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Records

351 documents · page 5 of 15

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
MMPOWER-3SS-31 (elamipretide)Phase 3ReportedRandomised, double-blind, placebo-controlled2182022Moderate
SURMOUNT-1-OLEprogramme recordTirzepatidePhase 3ReportedSingle-arm open-label2022Very low
MMPOWER-3-OLEprogramme recordSS-31 (elamipretide)Phase 3ReportedSingle-arm open-label2022Very low
CELIAC-PH3-CEDLARA-BODY-COMPprogramme recordLarazotide acetatePhase 3ReportedRandomised, double-blind, placebo-controlled2022Very low
SURMOUNT-1-ELDERLYprogramme recordTirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2022Very low
CELIAC-PH3-CEDLARA-REGIONAL-JPprogramme recordLarazotide acetatePhase 3ReportedRandomised, double-blind, placebo-controlled2022Very low
MMPOWER-3-BIOMARKERprogramme recordSS-31 (elamipretide)Phase 3ReportedRandomised, double-blind, placebo-controlled2022Very low
MMPOWER-3-ADHERENCEprogramme recordSS-31 (elamipretide)Phase 3ReportedObservational2022Very low
STEP-8-BIOMARKERprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2022Very low
STEP-1SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,9612021High
STEP-2SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,2102021High
STEP-3SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled6112021High
STEP-4SemaglutidePhase 3ReportedRandomised withdrawal8032021High
SURPASS-1TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled4782021High
SURPASS-2TirzepatidePhase 3ReportedRandomised, double-blind, active-controlled1,8792021High
SURPASS-3TirzepatidePhase 3ReportedRandomised, open-label, active-controlled1,4442021High
SURPASS-4TirzepatidePhase 3ReportedRandomised, open-label, active-controlled2,0022021High
AMPLITUDE-OExenatidePhase 3ReportedEvent-driven cardiovascular outcome trial4,0762021Moderate
STEP-1-ADHERENCEprogramme recordSemaglutidePhase 3ReportedObservational2021Very low
STEP-3-ELDERLYprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
SURPASS-2-ELDERLYprogramme recordTirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
AMPLITUDE-O-REGIONAL-JPprogramme recordExenatidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-1-BIOMARKERprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2021Very low
STEP-3-OLEprogramme recordSemaglutidePhase 3ReportedSingle-arm open-label2021Very low

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