Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3

Methodology|Interests|Funding|Corrections

Monograph series

Neuroactive peptides

Peptides supplied for cognitive, anxiolytic and sleep-related indications.

All series Incretin receptor agonists Amylin analogues Combinations and unimolecular co-agonists Growth-hormone axis Repair and regeneration Neuroactive peptides Immune modulators Mitochondrial and metabolic cofactors Melanocortin receptor agonists Reproductive-axis peptides

Monographs in this series

4 documents

DSIP

CEI-MN-038Neuroactive peptidesUnapproved, research supply3 assessed outcomesversion 1.2

DSIP was isolated on the hypothesis that it mediated sleep induction. Subsequent work has not established a receptor, a consistent pharmacological effect, or a physiological role, and the somnogenic activity that gave the peptide…

Very low24 May 2026
Epithalon

CEI-MN-039Neuroactive peptidesUnapproved, research supply3 assessed outcomesversion 1.2

Epithalon is supplied on the premise that it activates telomerase and thereby extends replicative lifespan, on the basis of cell-culture reports of telomerase induction in human somatic cells. The Institute notes that telomerase…

Very low26 Jan 2025
Selank

CEI-MN-037Neuroactive peptidesApproved1 assessed outcomeversion 1.0

Selank is reported to produce anxiolysis without sedation or dependence, attributed to modulation of GABAergic transmission and to inhibition of enkephalin degradation. It also carries the immunomodulatory activity of the tuftsin…

Low09 Feb 2026
Semax

CEI-MN-036Neuroactive peptidesApproved2 assessed outcomesversion 1.0

Semax is reported to increase expression of brain-derived neurotrophic factor and its receptor TrkB in rodent hippocampus, and to modulate monoaminergic transmission. Its approved Russian indications are ischaemic stroke and…

Low19 Apr 2026

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