Content

Applies to all synthetic peptides supplied as lyophilised powders. Establishes the Institute’s position that purity and content are independent quantities and that a certificate reporting one without the other is incomplete.

Applies to lyophilised peptide powders. Coulometric titration is specified rather than volumetric because sample availability is typically limited to a few milligrams.

Applies to all synthetic peptides supplied as salts, which in practice means all of them. Establishes that counter-ion identity and content are part of the specification and not a residue to be disregarded.

Applies to synthetic peptides and small molecules where solvents of ICH class 1 or 2 were used in synthesis or purification. The Institute records that this determination is absent from the research-supply channel entirely.