Cognitive performance and neuroprotection — compounds assessed
The 7 compounds the Institute assesses in cognitive performance and neuroprotection.
§4Compounds assessed
Compounds the Institute assesses in this indication, with the class of each and its overall certainty. A compound appears here whether or not the evidence supports its use, because recording that a compound has been studied and found wanting is as much part of the assessment as recording that one has not.
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Small randomised trials of intravenous and intranasal glutathione in Parkinson disease reported no significant benefit over placebo on motor endpoints — The available randomised evidence is negative rather than absent, which the Institute distinguishes.
Low -
No assessable evidence identified — —
Very low -
No assessable evidence identified — —
Very low -
No assessable randomised evidence identified — —
Very low -
Russian clinical studies report anxiolytic effect comparable to benzodiazepines without sedation or withdrawal — Downgraded for risk of bias and reporting limitations. A claim of benzodiazepine-equivalent anxiolysis without dependence would be a substantial…
Very low -
Russian clinical studies report functional improvement after ischaemic stroke and in cognitive disorders — Downgraded to very low for risk of bias and reporting limitations rather than for absence of studies. The Institute distinguishes these two reasons for…
Very low -
No evidence identified — —
Not rated
References cited on this page
References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.
- D’Hondt M, Bracke N, Taevernier L, Gevaert B, Verbeke F, Wynendaele E, De Spiegeleer B. Related impurities in peptide medicines. Journal of Pharmaceutical and Biomedical Analysis 2014;101:2–30. doi:10.1016/j.jpba.2014.06.012 · PMID 25044089
Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.