Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Trial records for Semaglutide

71 records for Semaglutide, of which 16 are published trials.

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Records

71 documents · page 1 of 3

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
STRIDESemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled7922025Moderate
ESSENCESemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled1,1972025Moderate
ESSENCE-PKprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2025Very low
STRIDE-QOLprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
ESSENCE-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2025Very low
STRIDE-REGIONAL-CNprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
STRIDE-REGIONAL-JPprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
ESSENCE-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2025Very low
STEP-HFpEF-DMSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled6162024Moderate
FLOWSemaglutidePhase 3ReportedEvent-driven kidney outcome trial3,5332024High
STEP-HFpEF-DM-BODY-COMPprogramme recordSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2024Very low
FLOW-PKprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2024Very low
FLOW-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2024Very low
FLOW-HEPATIC-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2024Very low
STEP-HFpEFSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled5292023Moderate
SELECTSemaglutidePhase 3ReportedEvent-driven cardiovascular outcome trial17,6042023High
STEP-HFpEF-HEPATIC-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2023Very low
SELECT-ADHERENCEprogramme recordSemaglutidePhase 3ReportedObservational2023Very low
STEP-HFpEF-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2023Very low
STEP-5SemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled3042022High
STEP-8SemaglutidePhase 3ReportedRandomised, double-blind, active-controlled3382022High
STEP-TEENSSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled2012022Moderate
STEP-5-PKprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low
STEP-8-RENAL-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2022Very low

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