Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Indication assessment · §4

Tendon, ligament and musculoskeletal soft-tissue injury — compounds assessed

The 2 compounds the Institute assesses in tendon, ligament and musculoskeletal soft-tissue injury.

Document identifier
CEI-IN-22/4
Series
Indication assessment
Version
2.3
Published
21 Aug 2024
Last reviewed
21 Aug 2024
Next review
21 Aug 2026
Identifier
10.71829/cei.ind.22
Certainty
Not rated
Cycle
2024 Q3
ICD-11
FB50
Category
Musculoskeletal

§4Compounds assessed

Compounds the Institute assesses in this indication, with the class of each and its overall certainty. A compound appears here whether or not the evidence supports its use, because recording that a compound has been studied and found wanting is as much part of the assessment as recording that one has not.

  • Synthetic pentadecapeptide derived from a gastric juice protein sequence0 contributing trialsfull monograph

    No randomised controlled human trial identified — The tendon and ligament claims that dominate discussion of this compound rest entirely on rodent models. There is no human trial.

    Very low
  • Acetylated heptapeptide fragment of thymosin beta-40 contributing trialsfull monograph

    No randomised controlled human trial identified — Preclinical rodent and equine work only.

    Very low

References cited on this page

References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.

  1. Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov DS, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D, Aralica G, Stupnisek M, Suran J, Barisic I, Dzidic S, Prkacin I. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Current Pharmaceutical Design 2011;17(16):1612–1632. doi:10.2174/138161211796196954 · PMID 21548867

Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.

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