Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Trial records reported in 2023 — page 2

55 records with a recorded report or completion year of 2023.

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Records

55 documents · page 2 of 3

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
ORFO-PH2-OBESITY-REGIONAL-CNprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled2023Very low
ORFO-PH2-OBESITY-REGIONAL-JPprogramme recordOrforglipronPhase 3ReportedRandomised, double-blind, placebo-controlled2023Very low
ORFO-PH2-T2DOrforglipronPhase 2ReportedRandomised, double-blind, placebo-controlled3832023Moderate
ORFO-PH2-T2D-DDIprogramme recordOrforglipronPhase 1ReportedRandomised crossover2023Very low
ORFO-PH2-T2D-HEPATIC-IMPprogramme recordOrforglipronPhase 1ReportedPhase 1 ascending dose2023Very low
ORFO-PH2-T2D-PKprogramme recordOrforglipronPhase 1ReportedPhase 1 ascending dose2023Very low
RETA-PH2-OBESITYRetatrutidePhase 2ReportedRandomised, double-blind, placebo-controlled3382023Moderate
RETA-PH2-OBESITY-DDIprogramme recordRetatrutidePhase 1ReportedRandomised crossover2023Very low
RETA-PH2-OBESITY-HEPATIC-IMPprogramme recordRetatrutidePhase 1ReportedPhase 1 ascending dose2023Very low
RETA-PH2-OBESITY-PKprogramme recordRetatrutidePhase 1ReportedPhase 1 ascending dose2023Very low
RETA-PH2-OBESITY-RENAL-IMPprogramme recordRetatrutidePhase 1ReportedPhase 1 ascending dose2023Very low
RETA-PH2-T2DRetatrutidePhase 2ReportedRandomised, double-blind, placebo-controlled2812023Moderate
RETA-PH2-T2D-DDIprogramme recordRetatrutidePhase 1ReportedRandomised crossover2023Very low
RETA-PH2-T2D-HEPATIC-IMPprogramme recordRetatrutidePhase 1ReportedPhase 1 ascending dose2023Very low
RETA-PH2-T2D-PKprogramme recordRetatrutidePhase 1ReportedPhase 1 ascending dose2023Very low
RETA-PH2-T2D-REGIONAL-CNprogramme recordRetatrutidePhase 3ReportedRandomised, double-blind, placebo-controlled2023Very low
RETA-PH2-T2D-RENAL-IMPprogramme recordRetatrutidePhase 1ReportedPhase 1 ascending dose2023Very low
SELECTSemaglutidePhase 3ReportedEvent-driven cardiovascular outcome trial17,6042023High
SELECT-ADHERENCEprogramme recordSemaglutidePhase 3ReportedObservational2023Very low
STEP-HFpEFSemaglutidePhase 3ReportedRandomised, double-blind, placebo-controlled5292023Moderate
STEP-HFpEF-DDIprogramme recordSemaglutidePhase 1ReportedRandomised crossover2023Very low
STEP-HFpEF-HEPATIC-IMPprogramme recordSemaglutidePhase 1ReportedPhase 1 ascending dose2023Very low
SURMOUNT-2TirzepatidePhase 3ReportedRandomised, double-blind, placebo-controlled9382023High
SURMOUNT-2-DDIprogramme recordTirzepatidePhase 1ReportedRandomised crossover2023Very low

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