Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial abstract · §3

SERM-DIAGNOSTIC — results

Primary endpoint, absolute and relative effect where derivable, and harms as reported.

Document identifier
CEI-TR-0146/3
Series
Trial abstract
Version
2.2
Published
11 Mar 2024
Last reviewed
11 Nov 2024
Next review
11 Nov 2026
Identifier
10.71829/cei.trial.146
Certainty
Moderate
Cycle
2024 Q1
Phase
Not applicable
Status
Reported

§3Results

§3.1Primary endpoint

Table 3. Primary endpoint as reported.

EndpointResult as reportedCertainty
Growth-hormone response to a growth-hormone-releasing hormone 1-29 challengeFormerly marketed as a diagnostic agent; withdrawn for commercial reasonsModerate
Reproduced from the published report. Where the report states a confidence interval the Institute reproduces it; where it does not, none is constructed.

§3.2Endpoint hierarchy

§3.3Harms as reported

Table 5. Adverse events for Sermorelin from the safety tables the Institute holds for this compound. Where a row names a different trial as its source, the figure is from that trial and not from this one.

EventActive, %Comparator, %Source trial
Injection-site reaction16.0Diagnostic-use data
FlushingReported transiently
DysgeusiaReported
HeadacheReported
NauseaReported at low incidence
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