Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial abstract · §3

IPA-PH2-POI — results

Primary endpoint, absolute and relative effect where derivable, and harms as reported.

Document identifier
CEI-TR-0101/3
Series
Trial abstract
Version
1.3
Published
02 Mar 2023
Last reviewed
02 Sep 2023
Next review
02 Sep 2025
Identifier
10.71829/cei.trial.101
Certainty
Not rated
Cycle
2023 Q1
Phase
Phase 2
Status
Terminated

§3Results

§3.1Primary endpoint

Table 3. Primary endpoint as reported.

EndpointResult as reportedCertainty
Time to recovery of gastrointestinal function after abdominal surgeryThe programme did not proceed. The Institute records that the only clinical development of this compound was in an indication unrelated to the uses under which it is supplied for researchNot rated
Reproduced from the published report. Where the report states a confidence interval the Institute reproduces it; where it does not, none is constructed.

§3.2Endpoint hierarchy

§3.3Harms as reported

Table 5. Adverse events for Ipamorelin from the safety tables the Institute holds for this compound. Where a row names a different trial as its source, the figure is from that trial and not from this one.

EventActive, %Comparator, %Source trial
Injection-site reactionReported
HeadacheReported
FlushingReported
Transient hungerLess than with non-selective secretagogues but reported
Fluid retentionExpected class effect
Glucose intoleranceExpected class effect; not systematically characterised
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