Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial abstract · §3

EPI-RU-ELDERLY — results

Primary endpoint, absolute and relative effect where derivable, and harms as reported.

Document identifier
CEI-TR-0110/3
Series
Trial abstract
Version
3.1
Published
24 Feb 2024
Last reviewed
24 Feb 2025
Next review
24 Feb 2027
Identifier
10.71829/cei.trial.110
Certainty
Not rated
Cycle
2024 Q1
Phase
Not applicable
Status
No retrievable report

§3Results

§3.1Primary endpoint

Table 3. Primary endpoint as reported.

EndpointResult as reportedCertainty
All-cause mortality and functional indices in an older cohortThe Institute has not been able to obtain a protocol, a randomisation procedure or an analysis plan for the reports circulated under this name and grades all claims in this programme very low certaintyNot rated
Reproduced from the published report. Where the report states a confidence interval the Institute reproduces it; where it does not, none is constructed.

§3.2Endpoint hierarchy

§3.3Harms as reported

Table 5. Adverse events for Epithalon from the safety tables the Institute holds for this compound. Where a row names a different trial as its source, the figure is from that trial and not from this one.

EventActive, %Comparator, %Source trial
No controlled safety datasetNone of adequate quality exists
Telomerase inductionIf the proposed telomerase mechanism operated as described, the implications for neoplasia would require careful study; none has been performed
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