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Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial register facet

Trial records for CagriSema (cagrilintide with semaglutide)

17 records for CagriSema (cagrilintide with semaglutide), of which 4 are published trials.

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Records

17 documents

Table 1. Trial records on this page. The table sorts on any column and filters on the controls above; both operate on the records shown on this page only.

RecordCompoundPhaseStatusDesignRandomisedYearCertainty
REDEFINE-1CagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled3,4172025Moderate
REDEFINE-2CagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled1,2062025Moderate
REDEFINE-1-ADHERENCEprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedObservational2025Very low
REDEFINE-2-OLEprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedSingle-arm open-label2025Very low
REDEFINE-2-ELDERLYprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
REDEFINE-1-ELDERLYprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
REDEFINE-2-BIOMARKERprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled2025Very low
REDEFINE-2-ADHERENCEprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedObservational2025Very low
CAGRI-SEMA-PH2-T2DCagriSema (cagrilintide with semaglutide)Phase 2ReportedRandomised, double-blind, active-controlled922023Low
CAGRI-SEMA-PH2-T2D-QOLprogramme recordCagriSema (cagrilintide with semaglutide)Phase 2ReportedRandomised, double-blind, placebo-controlled2023Very low
CAGRI-SEMA-PH2-T2D-REGIONAL-CNprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled2023Very low
CAGRI-SEMA-PH2-T2D-REGIONAL-JPprogramme recordCagriSema (cagrilintide with semaglutide)Phase 3ReportedRandomised, double-blind, placebo-controlled2023Very low
CAGRI-SEMA-PH2-T2D-BODY-COMPprogramme recordCagriSema (cagrilintide with semaglutide)Phase 2ReportedRandomised, double-blind, placebo-controlled2023Very low
REDEFINE-4CagriSema (cagrilintide with semaglutide)Phase 3OngoingRandomised, double-blind, active-controlledNot rated
REDEFINE-4-RENAL-IMPprogramme recordCagriSema (cagrilintide with semaglutide)Phase 1OngoingPhase 1 ascending doseVery low
REDEFINE-4-PKprogramme recordCagriSema (cagrilintide with semaglutide)Phase 1OngoingPhase 1 ascending doseVery low
REDEFINE-4-DDIprogramme recordCagriSema (cagrilintide with semaglutide)Phase 1OngoingRandomised crossoverVery low
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