Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Trial abstract · §3

BPC-PH2-UC — results

Primary endpoint, absolute and relative effect where derivable, and harms as reported.

Document identifier
CEI-TR-0111/3
Series
Trial abstract
Version
3.4
Published
15 Feb 2024
Last reviewed
15 Dec 2024
Next review
15 Dec 2026
Identifier
10.71829/cei.trial.111
Certainty
Not rated
Cycle
2024 Q1
Phase
Phase 2
Status
No retrievable report

§3Results

§3.1Primary endpoint

Table 3. Primary endpoint as reported.

EndpointResult as reportedCertainty
Clinical remission in ulcerative colitisThe Institute has identified references to a clinical programme under this compound but has not obtained a published report, and grades all human claims very low certainty on that basisNot rated
Reproduced from the published report. Where the report states a confidence interval the Institute reproduces it; where it does not, none is constructed.

§3.2Endpoint hierarchy

§3.3Harms as reported

Table 5. Adverse events for BPC-157 from the safety tables the Institute holds for this compound. Where a row names a different trial as its source, the figure is from that trial and not from this one.

EventActive, %Comparator, %Source trial
Injection-site reactionReported anecdotally; no controlled safety dataset exists
No dose-limiting toxicity in rodent studiesPreclinical studies report a wide therapeutic index; this does not establish human safety
Angiogenic mechanismIf the proposed angiogenic mechanism is real, its consequences in the presence of occult neoplasia have not been studied at all
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