Weight-reducing agents for obstructive sleep apnoea — amendment log
Every change made since protocol registration, with its date and reason.
§5Amendment log
Every change made to this review after protocol registration is recorded below with its date and its reason. A change that is not in this log did not happen. The Institute publishes the log in full, including changes that did not alter a conclusion, because a reader cannot judge which changes matter unless all of them are visible.
§5.1Amendment log
Table 9. Amendments to this review since protocol registration.
| Date | Version | Amendment | Record |
|---|---|---|---|
| 01 Jan 2026 | 0.1 | Protocol registered | The review protocol was registered with the Institute’s secretariat before the search was executed. No change to the review question was made after registration. |
| 27 Apr 2026 | 2.1 | Certainty rating revised | The certainty rating for one outcome was revised following the addition of a contributing study. The rationale is recorded in the certainty assessment section. |
| 08 Jul 2026 | 2.2 | Study reclassified | A study previously included was reclassified as ineligible following retrieval of the full report. The quantitative synthesis was re-run without it. |
| Current version 2.3, ratified in the 2026 Q1 assessment cycle. | |||
§5.2Clinical study report requests
Table 10. Clinical study reports requested for the contributing trials, and the outcome of each request. Refusals are recorded because a review that does not record them presents the sponsor's disclosure decision as the Institute's own.
| Trial | Requested | Outcome |
|---|---|---|
| SURMOUNT-OSA-1 | 17 Sep 2025 | Refused |
| SURMOUNT-OSA-2 | 10 Oct 2025 | Partially supplied |
| SCALE-SLEEP-APNOEA | 03 Nov 2025 | Supplied on request |
§5.3Superseded versions
Superseded versions of this review remain published at a stable address, are marked as superseded, and link forward to the current version. The current version links back to each of them. That practice was adopted following a submission that a document cited in the literature must remain retrievable in the form in which it was cited; the reasoning is published on the corrections policy disposition page.