Public comment period · §3
Draft standard CEI-MS-02: Confirmation of peptide identity by… — disposition
The disposition of every submission and the amendments that resulted.
§3Disposition and amendments
§3.1Disposition table
Table 1. Every submission with its disposition. Each row links to the submission in full.
| Reference | Respondent | Point raised | Disposition |
|---|---|---|---|
| DRAFT-LCMSMS-IDENT/002 | Dr Fenella Lavrentiev | The scope does not say which materials the standard excludes | Accepted |
| DRAFT-LCMSMS-IDENT/001 | Ludmila Brackenridge | A determination does not record the version of the standard it was made under | Accepted |
| DRAFT-LCMSMS-IDENT/005 | Dr Valentin Castellanos-Reid | The standard would be applied more consistently with a worked example | Accepted |
| DRAFT-LCMSMS-IDENT/006 | Dr Frideswide Nordhagen | The document is unreadable without specialist training | Accepted in part |
| DRAFT-LCMSMS-IDENT/004 | Dr Matthias Whitmarsh-Obi | A system suitability criterion is unachievable on instrumentation in general use | Accepted in part |
| DRAFT-LCMSMS-IDENT/003 | Dr Wilhelmina Wintringham | The limitations section states what the method cannot do but not what a reader will wrongly conclude | Accepted |
| 6 submissions in total. | |||
§3.2Summary by disposition
Table 2. Counts by disposition, with the meaning of each.
| Disposition | Count | Meaning |
|---|---|---|
| Accepted | 4 | The submission is accepted and the draft is amended as proposed. The amendment is recorded in the amendment log of the document it changed and is traceable to the numbered submission. |
| Accepted in part | 2 | Part of the submission is accepted and part is not. The secretariat response states which part is which and on what ground the remainder was declined. |
| Noted, no amendment | 0 | The submission raises a point the Institute accepts but that does not require a change to the draft, most often because the draft already states it elsewhere. The location is given in the response. |
| Not accepted | 0 | The submission is not accepted. The secretariat response gives the reason. A submission that is not accepted remains published in full; the Institute does not remove a submission because it disagrees with it. |
§3.3Resulting amendments
- The scope does not say which materials the standard excludes — arising from DRAFT-LCMSMS-IDENT/002. The scope now states both what the standard applies to and what it does not, with the excluded classes named and, where another standard covers them, cross-referenced.
- A determination does not record the version of the standard it was made under — arising from DRAFT-LCMSMS-IDENT/001. Every determination reported under this standard now carries the standard identifier and version on its face, and a claim of conformance that does not identify the version is recorded by the Institute as not conformant.
- The standard would be applied more consistently with a worked example — arising from DRAFT-LCMSMS-IDENT/005. A worked example is added showing the same primary data treated two ways, with both resulting figures stated and the difference between them quantified, so that the consequence of the misapplication is visible rather than described.
- The document is unreadable without specialist training — arising from DRAFT-LCMSMS-IDENT/006. Every document now opens with a plain-language summary of not more than 150 words, placed above the technical abstract and carrying the same certainty language, so that the two cannot diverge.
- A system suitability criterion is unachievable on instrumentation in general use — arising from DRAFT-LCMSMS-IDENT/004. The suitability criterion is now stated at two levels, a general level achievable on instrumentation in common use and a stricter level required only where the standard is applied to the discrimination named in the scope, with the reason for the difference…
- The limitations section states what the method cannot do but not what a reader will wrongly conclude — arising from DRAFT-LCMSMS-IDENT/003. The limitations section now lists the specific conclusions a conformant determination does not support, each stated as a sentence a reader could otherwise have written, and the list is placed before the references rather than in an annex.
References cited on this page
References are numbered in order of first citation in this document. Each superscript in the text links to its entry below.
- International Organization for Standardization. ISO/IEC 17025:2017 General Requirements for the Competence of Testing and Calibration Laboratories. ISO/IEC Standard 2017;3rd edition. identifier not held by the Institute
Identifiers are reproduced only where the Institute holds them. Where a digital object identifier or PubMed identifier is not shown, the Institute has recorded the journal and year and has not constructed an identifier.
Compound Evidence Institute · CEI-CP-084/3 · https://compoundevidence.com/comment-periods/draft-lcmsms-identity-standard/disposition/ · retrieved 30 July 2026