Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Public comment period · Document series

Draft certainty index

Consultation on the draft certainty index, a cross-cutting finding aid that lists every assessed outcome in the document set by its certainty rating. The index makes it possible to see, in one place, how much of the Institute's output rests on low or very low…

Document identifier
CEI-CP-038
Series
Public comment period
Version
1.0
Published
10 Jul 2026
Last reviewed
10 Jul 2026
Next review
10 Jul 2027
Identifier
10.71829/cei.cp.38
Certainty
Not rated
Cycle
2026 Q3
Window
10 Jul 2026 – 07 Aug 2026
Status
Open
Submissions
15

§1Consultation and window

§1.1Window

Opened
10 July 2026
Closed
7 August 2026
Duration
28 days
Status
Open — submissions are being received
Document under consultation
Document series
Submissions received
15

§1.2Consultation questions

The secretariat put the following questions. A submission was not required to address them and several did not; the questions record what the Institute was uncertain about rather than restricting what a respondent could raise.

  1. Does an index organised by certainty invite comparison between ratings assigned in different domains that are not directly comparable?
  2. Should the index show the reason for each downgrade alongside the rating?
  3. Is the index a document in its own right, requiring its own version and review date, or a generated view of other documents?

§1.3How a submission is handled

  • Every submission is signed. The Institute publishes no anonymous submission.
  • Every submission carries a declared interest. A declaration of no interest is itself a declaration and is recorded as one. A declaration is not a disqualification and the Institute has never given a submission less weight on that ground.
  • A submission from an employee of a marketing-authorisation holder is identified as an industry submission on its face, following a unanimous consultation on the conflicts policy.
  • Every submission receives a secretariat response and a disposition. Submissions that are not accepted remain published in full; the Institute does not remove a submission because it disagrees with it.
  • There is no voting, no reputation score, no reply thread and no editing after receipt.

§1.4Making a submission

Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.