Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Consultation record

Submissions accepted — page 6

The submission is accepted and the draft is amended as proposed. The amendment is recorded in the amendment log of the document it changed and is traceable to the numbered submission.

Submissions

681 documents · page 6 of 23

Table 1. Submissions with this disposition, on this page.

ReferenceConsultationRespondentPoint raised
DRAFT-ADOLESCENT-S/001Draft synthesis: incretin receptor agonists in adolescentsDr Eulalia Sonnenberg-EzeDoses differing several-fold are pooled without examining dose-response
DRAFT-ADOLESCENT-S/011Draft synthesis: incretin receptor agonists in adolescentsDr Frideswide Grünbaum-SowandeRegistered trials that never reported are not counted anywhere in the review
DRAFT-ADOLESCENT-S/012Draft synthesis: incretin receptor agonists in adolescentsDr Delphine RavensworthThe conclusion is stated more strongly than the certainty rating supports
DRAFT-ADOLESCENT-S/014Draft synthesis: incretin receptor agonists in adolescentsDr Jozef Brandvold-AchterbergEfficacy outcomes are rated for certainty and harms are not
DRAFT-ANALYTICAL-S/005Draft analytical review: surveys of unregulated peptide supplyDr Liesbeth Nyquist-ObioraAbsence of evidence is presented in a form a reader will take as negative evidence
DRAFT-ANALYTICAL-S/006Draft analytical review: surveys of unregulated peptide supplyDr Eulalia Sonnenberg-EzeThe same concept is given three different names in one document
DRAFT-ANALYTICAL-S/008Draft analytical review: surveys of unregulated peptide supplyHortensia HollingworthDoses differing several-fold are pooled without examining dose-response
DRAFT-ANALYTICAL-S/004Draft analytical review: surveys of unregulated peptide supplyDr Zofia PetrossianThe conclusion is stated more strongly than the certainty rating supports
DRAFT-ANALYTICAL-S/010Draft analytical review: surveys of unregulated peptide supplyDr Melisande Kirkpatrick-OlaAnalytical surveys are treated as evidence about suppliers when they establish only what was in a…
DRAFT-ANALYTICAL-S/001Draft analytical review: surveys of unregulated peptide supplyDr Hyacinth Drakeford-AmadiEfficacy outcomes are rated for certainty and harms are not
DRAFT-REGISTRY-STR/003Draft structure of the document registryDr Vittoria YlönenThe search date is not on the face of the document
DRAFT-REGISTRY-STR/002Draft structure of the document registryDr Katarzyna Oppenheimer-Ade industryTwo factual descriptions of the sponsor's programme are inaccurate
DRAFT-REGISTRY-STR/009Draft structure of the document registryDr Delphine TrelawneyAbsence of evidence is presented in a form a reader will take as negative evidence
DRAFT-REGISTRY-STR/008Draft structure of the document registryDr Lorcan TrelawneyQuantitative claims are reproduced without the method that produced them
DRAFT-TOOLS-DISCLA/016Draft terms for the Institute’s calculatorsRosalind PetrossianAn industry submission should be identifiable without reading the declared interest
DRAFT-TOOLS-DISCLA/009Draft terms for the Institute’s calculatorsDr Fenella Steenkamp-FerreiraThe same concept is given three different names in one document
DRAFT-TOOLS-DISCLA/013Draft terms for the Institute’s calculatorsDr Ngozi ZetterlundThe position of a contributor who withdraws consent is not stated
DRAFT-TOOLS-DISCLA/014Draft terms for the Institute’s calculatorsKolawole Jankowiak-OseiWhether external reviewers are paid is not stated
DRAFT-TOOLS-DISCLA/007Draft terms for the Institute’s calculatorsXiomara Fairweather-DuruThe terms on which the documents may be reused are not stated
DRAFT-TOOLS-DISCLA/018Draft terms for the Institute’s calculatorsDr Georgiana MountstephenWhat the site collects about a reader is not stated in terms a reader can check
DRAFT-TOOLS-DISCLA/017Draft terms for the Institute’s calculatorsDr Jolanta UttridgeAbsence of evidence is presented in a form a reader will take as negative evidence
DRAFT-ORFORGLIPRON/004Draft monograph: orforglipronDr Ulysses Bellingham-OjoEvidence for one member of the class is presented as evidence for this compound
DRAFT-ORFORGLIPRON/006Draft monograph: orforglipronDr Thaddeus Isaksen-BalogunThe analytical section assumes a reference standard that is not generally available
DRAFT-ORFORGLIPRON/007Draft monograph: orforglipronProfessor Chukwuemeka Rasmussen-AdeyemiThe monograph does not tell a reader that a stated mass may be substantially counter-ion and water
DRAFT-ORFORGLIPRON/009Draft monograph: orforglipronBrigitta Grünbaum-SowandeThe pharmacokinetic section does not connect half-life to the dosing schedule
DRAFT-ORFORGLIPRON/010Draft monograph: orforglipronDr Quentin ZimmerthalThe population to which the headline estimate applies is not stated with the estimate
DRAFT-ORFORGLIPRON/001Draft monograph: orforglipronDr Wojciech Kaltenbach-MensahMechanistic claims for a peptide fragment are carried without evidence that the fragment acts as…
DRAFT-DANUGLIPRON-/001Draft monograph: danuglipronDr Georgiana MountstephenThe certainty rating for the principal assessed outcome cannot be traced to the contributing trials
DRAFT-DANUGLIPRON-/002Draft monograph: danuglipronDr Jolanta UttridgeThe indication table mixes approved indications with uses for which the compound is merely supplied
DRAFT-METHODOLOGY-/013Draft methodology document, version 4Kolawole Jankowiak-OseiThe same concept is given three different names in one document

page 6 of 23

Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.