Defined term · Analytical chemistry
Limit of detection
The lowest concentration at which the presence of a species can be distinguished from noise. Lower than the limit of quantitation and not a basis for a numerical result.
§1Limit of detection
§1.1Also known as
LOD
§1.2Category
Analytical chemistry — Terms describing the determination of identity, purity, content and quality.
§1.3Related terms
- Limit of quantitation — The lowest concentration at which a determination can be made with stated precision and accuracy. An impurity below the limit is not absent; it is unquantified.
Compound Evidence Institute · CEI-GT-159 · https://compoundevidence.com/glossary/limit-of-detection/ · retrieved 30 July 2026