Independent · non-commercial · publishes on a quarterly cycle|Current cycle 2026 Q3
Methodology|Interests|Funding|Corrections
Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Trial design and conduct

Intercurrent event

An event occurring after randomisation that affects the interpretation of the outcome, such as treatment discontinuation, rescue medication or death. The strategy for handling each is part of the…

Document identifier
CEI-GT-054
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Intercurrent event

§1.2Category

Trial design and conduct — Terms describing how a clinical study is constructed and run.

§1.3Related terms

  • Estimand — A precise statement of the quantity a trial is estimating, including how intercurrent events such as discontinuation or rescue therapy are handled. Two trials reporting…
Compound Evidence Institute · CEI-GT-054 · https://compoundevidence.com/glossary/intercurrent-event/ · retrieved 30 July 2026
Nothing published by the Institute is medical advice, a diagnosis, a prescription, a treatment recommendation or a purchasing recommendation. Compounds supplied for research use are not approved for human or veterinary use in any jurisdiction, and a favourable analytical assessment of a supplier is not a statement that any product is safe or effective. The Institute publishes certainty ratings and never recommendations. No telephone number, messaging handle or ordering channel appears anywhere on this site.