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Document set current to 30 July 2026
Defined term · Pharmacology

Incretin

A gut-derived hormone that potentiates insulin secretion in response to nutrient intake. The two principal human incretins are glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide.

Document identifier
CEI-GT-117
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Incretin

§1.2Category

Pharmacology — Terms describing how a compound acts and how the body handles it.

§1.3Related terms

  • GLP-1 receptor agonist — A compound activating the glucagon-like peptide-1 receptor, a class B G protein-coupled receptor signalling principally through Gαs. Effects include glucose-dependent…
  • GIP — Glucose-dependent insulinotropic polypeptide, the second human incretin. Its contribution to the effects of dual agonists is substantially supported and not fully…
Compound Evidence Institute · CEI-GT-117 · https://compoundevidence.com/glossary/incretin/ · retrieved 30 July 2026
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