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Compound Evidence InstituteEvidence synthesis · established 2023Graded assessments of compounds, trials, methods and supply
Document set current to 30 July 2026
Defined term · Pharmacology

Clearance

The volume of plasma cleared of a compound per unit time. Together with volume of distribution it determines half-life.

Document identifier
CEI-GT-112
Series
Defined term
Version
1.0
Published
30 Jul 2026
Last reviewed
30 Jul 2026
Certainty
Not rated

§1Clearance

§1.2Category

Pharmacology — Terms describing how a compound acts and how the body handles it.

§1.3Related terms

  • Half-life — The time for a plasma concentration to fall by half during the terminal elimination phase. Determines dosing interval, time to steady state and the time required for…
Compound Evidence Institute · CEI-GT-112 · https://compoundevidence.com/glossary/clearance/ · retrieved 30 July 2026
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